The 28-year-old will be hoping to put a miserable domestic campaign with United behind him when his country take on Switzerland, Honduras and France in Group E.
Felipe Caicedo, now with United Arab Emirates club Al Jazira, has also been included, as has 35-year-old midfielder Edison Mendez, Ecuador’s third-most capped player.
Head coach Reinaldo Rueda must finalise his squad before the cut-off point of 2 June.
Goalkeepers: Maximo Banguera (Barcelona, Ecuador), Adrian Bone (El Nacional), Alexander Dominguez (Liga de Quito)
Defenders: Gabriel Achilier (Emelec), Walter Ayovi (Pachuca), Oscar Bagui (Emelec), Frickson Erazo (Flamengo), Jorge Guagua (Emelec), John Narvaez (Emelec), Juan Carlos Paredes (Barcelona, Ecuador), Cristian Ramirez (Fortuna Duesseldorf)
Midfielders: Michael Arroyo (Atlante), Segundo Castillo (Al Hilal), Carlos Gruezo (Stuttgart), Renato Ibarra (Vitesse Arnhem), Fidel Martinez (Tijuana), Edison Mendez (Santa Fe), Oswaldo Minda (Chivas USA), Christian Noboa (Dynamo Moscow), Pedro Quinonez (Emelec), Luis Saritama (Barcelona, Ecuador), Antonio Valencia (Manchester United)
Forwards: Jaime Ayovi (Tijuana), Felipe Caicedo (Al-Jazira), Angel Mena (Emelec), Jefferson Montero (Morelia), Cristian Penilla (Barcelona, Ecuador), Joao Rojas (Cruz Azul), Enner Valencia (Pachuca), Armando Wila (Universidad Catolica)