Blues boss Rafael Benitez is poised to make a host of changes from the starting XI which beat Rubin Kazan 3-1 in the Europa League on Thursday. Defensive duo Gary Cahill (knee) and Ashley Cole (hamstring) both remain sidelined.
John Obi Mikel, Eden Hazard and Oscar could all be recalled, while Demba Ba may replace Fernando Torres up front, despite the Spaniard scoring against the Russian side. Long-term injury absentee Oriol Romeu (knee) remains out injured.
As for the Black Cats, Paulo Di Canio will be without influential duo Lee Cattermole (knee) and Steven Fletcher (ankle) for the remainder of the season. Sebastian Larsson is likely to be handed a starting berth.
Upfront, Connor Wickham is pushing Danny Graham for a starting spot. However, defensive pair Wes Brown (knee) and Carlos Cuellar (ankle) are both still unavailable.
Cech, Azpilicueta, Ivanovic, Luiz, Bertrand, Ramires, Mikel, Hazard, Oscar, Mata and Ba might probably be starting for Chelsea whereas Sunderland probably starts with Mignolet, Gardner, O’Shea, Bramble, Rose, Johnson, N’Diaye, Larsson, McClean, Sessegnon and Graham.
The match will kick off at 14hours GMT with N. Swarbrick as the referee.